Ontology highlight
ABSTRACT:
SUBMITTER: Tatetsu H
PROVIDER: S-EPMC4823161 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Tatetsu Hiro H Kong Nikki R NR Chong Gao G Amabile Giovanni G Tenen Daniel G DG Chai Li L
Gene 20160216 2
There is a growing body of evidence supporting that cancer cells share many similarities with embryonic stem cells (ESCs). For example, aggressive cancers and ESCs share a common gene expression signature that includes hundreds of genes. Since ESC genes are not present in most adult tissues, they could be ideal candidate targets for cancer-specific diagnosis and treatment. This is an exciting cancer-targeting model. The major hurdle to test this model is to identify the key factors/pathway(s) wi ...[more]