Ontology highlight
ABSTRACT:
SUBMITTER: Du WW
PROVIDER: S-EPMC4824104 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Du William W WW Yang Weining W Liu Elizabeth E Yang Zhenguo Z Dhaliwal Preet P Yang Burton B BB
Nucleic acids research 20160209 6
Most RNAs generated by the human genome have no protein-coding ability and are termed non-coding RNAs. Among these include circular RNAs, which include exonic circular RNAs (circRNA), mainly found in the cytoplasm, and intronic RNAs (ciRNA), predominantly detected in the nucleus. The biological functions of circular RNAs remain largely unknown, although ciRNAs have been reported to promote gene transcription, while circRNAs may function as microRNA sponges. We demonstrate that the circular RNA c ...[more]