Ontology highlight
ABSTRACT:
SUBMITTER: Boerneke MA
PROVIDER: S-EPMC4824544 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Angewandte Chemie (International ed. in English) 20160223 12
RNA nanotechnology uses RNA structural motifs to build nanosized architectures that assemble through selective base-pair interactions. Herein, we report the crystal-structure-guided design of highly stable RNA nanotriangles that self-assemble cooperatively from short oligonucleotides. The crystal structure of an 81 nucleotide nanotriangle determined at 2.6 Å resolution reveals the so-far smallest circularly closed nanoobject made entirely of double-stranded RNA. The assembly of the nanotriangle ...[more]