Ontology highlight
ABSTRACT:
SUBMITTER: Prieto P
PROVIDER: S-EPMC4824594 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Prieto Patricia P Rosales-Mendoza César Eduardo CE Terrón Verónica V Toledano Víctor V Cuadrado Antonio A Cuadrado Antonio A López-Collazo Eduardo E Bannenberg Gerard G Martín-Sanz Paloma P Fernández-Velasco María M Boscá Lisardo L
Autophagy 20150101 10
The resolution of inflammation is an active process driven by specialized pro-resolving lipid mediators, such as 15-epi-LXA4 and resolvin D1 (RvD1), that promote tissue regeneration. Macrophages regulate the innate immune response being key players during the resolution phase to avoid chronic inflammatory pathologies. Their half-life is tightly regulated to accomplish its phagocytic function, allowing the complete cleaning of the affected area. The balance between apoptosis and autophagy appears ...[more]