Ontology highlight
ABSTRACT:
SUBMITTER: Barisic M
PROVIDER: S-EPMC4825607 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Barisic Marin M Maiato Helder H
Cell cycle (Georgetown, Tex.) 20150101 21
Equal distribution of the genetic material during cell division relies on efficient congression of chromosomes to the metaphase plate. Prior to their alignment, the Dynein motor recruited to kinetochores transports a fraction of laterally-attached chromosomes along microtubules toward the spindle poles. By doing that, Dynein not only contributes to chromosome movements, but also prevents premature stabilization of end-on kinetochore-microtubule attachments. This is achieved by 2 parallel mechani ...[more]