Ontology highlight
ABSTRACT:
SUBMITTER: Yu D
PROVIDER: S-EPMC4826108 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Yu Dong D Hui Yiming Y Zai Xiaodong X Xu Junjie J Liang Long L Wang Bingxiang B Yue Junjie J Li Shanhu S
Virulence 20150603 8
The Brucella abortus strain 104M, a spontaneously attenuated strain, has been used as a vaccine strain in humans against brucellosis for 6 decades in China. Despite many studies, the molecular mechanisms that cause the attenuation are still unclear. Here, we determined the whole-genome sequence of 104M and conducted a comprehensive comparative analysis against the whole genome sequences of the virulent strain, A13334, and other reference strains. This analysis revealed a highly similar genome st ...[more]