Ontology highlight
ABSTRACT:
SUBMITTER: Choi PW
PROVIDER: S-EPMC4826193 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Choi Pui-Wah PW Yang Junzheng J Ng Shu-Kay SK Feltmate Colleen C Muto Michael G MG Hasselblatt Kathleen K Lafferty-Whyte Kyle K JeBailey Lellean L MacConaill Laura L Welch William R WR Fong Wing-Ping WP Berkowitz Ross S RS Ng Shu-Wing SW
Oncotarget 20160101 4
Increased inclusion cyst formation in the ovary is associated with ovarian cancer development. We employed in vitro three-dimensional (3D) organotypic models formed by normal human ovarian surface epithelial (OSE) cells and ovarian cancer cells to study the morphologies of normal and cancerous ovarian cortical inclusion cysts and the molecular changes during their transitions into stromal microenvironment. When compared with normal cysts that expressed tenascin, the cancerous cysts expressed hig ...[more]