Ontology highlight
ABSTRACT:
SUBMITTER: Lorenzi M
PROVIDER: S-EPMC4827392 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Lorenzi Marco M Simpson Ivor J IJ Mendelson Alex F AF Vos Sjoerd B SB Cardoso M Jorge MJ Modat Marc M Schott Jonathan M JM Ourselin Sebastien S
Scientific reports 20160411
The joint analysis of brain atrophy measured with magnetic resonance imaging (MRI) and hypometabolism measured with positron emission tomography with fluorodeoxyglucose (FDG-PET) is of primary importance in developing models of pathological changes in Alzheimer's disease (AD). Most of the current multimodal analyses in AD assume a local (spatially overlapping) relationship between MR and FDG-PET intensities. However, it is well known that atrophy and hypometabolism are prominent in different ana ...[more]