Ontology highlight
ABSTRACT:
SUBMITTER: Durruthy-Durruthy J
PROVIDER: S-EPMC4827613 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Durruthy-Durruthy Jens J Sebastiano Vittorio V Wossidlo Mark M Cepeda Diana D Cui Jun J Grow Edward J EJ Davila Jonathan J Mall Moritz M Wong Wing H WH Wysocka Joanna J Au Kin Fai KF Reijo Pera Renee A RA
Nature genetics 20151123 1
Long intergenic noncoding RNAs (lincRNAs) are derived from thousands of loci in mammalian genomes and are frequently enriched in transposable elements (TEs). Although families of TE-derived lincRNAs have recently been implicated in the regulation of pluripotency, little is known of the specific functions of individual family members. Here we characterize three new individual TE-derived human lincRNAs, human pluripotency-associated transcripts 2, 3 and 5 (HPAT2, HPAT3 and HPAT5). Loss-of-function ...[more]