Unknown

Dataset Information

0

Left Atrial Appendage Ligation And Exclusion Technology In The Incubator.


ABSTRACT: Stroke is the most feared complication of atrial fibrillation (AF). Targeting the left atrial appendage (LAA) mechanically is attractive as a means to simultaneously reduce stroke risk, the need for anticoagulation, and hemorrhagic complications in patients with non-valvular AF. The results of the PROTECT-AF and PREVAIL randomized clinical trials support this approach as a viable therapeutic alternative to warfarin in selected patients and add to accumulating evidence regarding the importance of the LAA in thromboembolism in AF. A number of devices for percutaneous LAA closure are under investigation or development. In this article, key design features of these ligation and exclusion technologies will be discussed, with a focus on aspects of LAA morphology, relational anatomy, thrombosis, and thromboembolism relevant for successful device development and deployment.

SUBMITTER: Syed FF 

PROVIDER: S-EPMC4829965 | biostudies-literature |

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC5135162 | biostudies-other
| S-EPMC4458506 | biostudies-literature
| S-EPMC8501246 | biostudies-literature
| S-EPMC3480004 | biostudies-literature
| S-EPMC9909459 | biostudies-literature
| S-EPMC8183657 | biostudies-literature
2018-10-19 | GSE117801 | GEO
| S-EPMC8420938 | biostudies-literature
| S-EPMC5791500 | biostudies-literature