Ontology highlight
ABSTRACT:
SUBMITTER: Zhou M
PROVIDER: S-EPMC4832137 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Stem cells (Dayton, Ohio) 20151117 1
Cancer stem cells (CSCs) are a subpopulation of neoplastic cells with self-renewal capacity and limitless proliferative potential as well as high invasion and migration capacity. These cells are commonly associated with epithelial-mesenchymal transition (EMT), which is also critical for tumor metastasis. Recent studies illustrate a direct link between EMT and stemness of cancer cells. Long non-coding RNAs (lncRNAs) have emerged as important new players in the regulation of multiple cellular proc ...[more]