Ontology highlight
ABSTRACT:
SUBMITTER: Badr DM
PROVIDER: S-EPMC4834195 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Badr Doaa M DM Hafez Hafez F HF Agha Azza M AM Shouman Samia A SA
Oxidative medicine and cellular longevity 20160329
α-Tocopheryl succinate (α-TOS), a mitochondria-targeting agent, induces apoptosis in malignant cells in vitro and in vivo. Selenite is a nutritional supplement that has been shown to stimulate apoptosis in cancer cells. This study was designed to investigate the cytotoxic effect of combined treatment of α-TOS and sodium selenite (SSe) in vitro and in vivo and to explore their effect on apoptosis and autophagy in breast cancer. The type of interaction between α-TOS and SSe was evaluated and level ...[more]