Ontology highlight
ABSTRACT:
SUBMITTER: Birger RB
PROVIDER: S-EPMC4835347 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Birger Ruthie B RB Kouyos Roger D RD Cohen Ted T Griffiths Emily C EC Huijben Silvie S Mina Michael J MJ Volkova Victoriya V Grenfell Bryan B Metcalf C Jessica E CJE
Trends in microbiology 20150529 9
Across a range of pathogens, resistance to chemotherapy is a growing problem in both public health and animal health. Despite the ubiquity of coinfection, and its potential effects on within-host biology, the role played by coinfecting pathogens on the evolution of resistance and efficacy of antimicrobial chemotherapy is rarely considered. In this review, we provide an overview of the mechanisms of interaction of coinfecting pathogens, ranging from immune modulation and resource modulation, to d ...[more]