Unknown

Dataset Information

0

Modular Assembly Approach to Engineer Geometrically Precise Cardiovascular Tissue.

ABSTRACT: This modular assembly approach to microfabricate functional cardiovascular tissue composites enables quantitative assessment of the effects of microarchitecture on cellular function. Cardiac and endothelial modules are micromolded separately, designed to direct cardiomyocyte alignment and anisotropic contraction or vascular network formation. Assembled cardiovascular tissue composites contract synchronously, facilitating the use of this tissue-engineering platform to study structure-function relationships in the heart.

SUBMITTER: Lee BW 

PROVIDER: S-EPMC4836958 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Modular Assembly Approach to Engineer Geometrically Precise Cardiovascular Tissue.

Lee Benjamin W BW   Liu Bohao B   Pluchinsky Adam A   Kim Nathan N   Eng George G   Vunjak-Novakovic Gordana G  

Advanced healthcare materials 20160210 8

This modular assembly approach to microfabricate functional cardiovascular tissue composites enables quantitative assessment of the effects of microarchitecture on cellular function. Cardiac and endothelial modules are micromolded separately, designed to direct cardiomyocyte alignment and anisotropic contraction or vascular network formation. Assembled cardiovascular tissue composites contract synchronously, facilitating the use of this tissue-engineering platform to study structure-function rel  ...[more]

Similar Datasets

Unknown Modular Component Assembly Approach to Microtia Reconstruction.
| S-EPMC4968401 | biostudies-literature
Unknown A Modular Strategy to Engineer Complex Tissues and Organs.
| S-EPMC5978945 | biostudies-literature
Unknown In situ assembly of linked geometrically coupled microdevices.
| S-EPMC2629335 | biostudies-literature
Unknown Assembly of complex cell microenvironments using geometrically docked hydrogel shapes.
| S-EPMC3607001 | biostudies-literature
Unknown A Modular Assembly of Spinal Cord-Like Tissue Allows Targeted Tissue Repair in the Transected Spinal Cord.
| S-EPMC6145267 | biostudies-literature
Unknown Selecting precise reference normal tissue samples for cancer research using a deep learning approach.
| S-EPMC6357350 | biostudies-literature
Transcriptomics A Systems Approach to Reverse Engineer Lifespan Extension by Dietary Restriction
2016-01-22 | GSE77111 | GEO
Other Precise Transcript Reconstruction with End-Guided Assembly
2022-01-08 | GSE189482 | GEO
Unknown Neural layer self-assembly in geometrically confined rat and human 3D cultures.
| S-EPMC6908307 | biostudies-literature
Unknown Modular Approach to Spintronics.
| S-EPMC4464157 | biostudies-literature