Pathology interface for the molecular analysis of tissue by mass spectrometry.
Ontology highlight
ABSTRACT: Background
Imaging mass spectrometry (IMS) generates molecular images directly from tissue sections to provide better diagnostic insights and expand the capabilities of clinical anatomic pathology. Although IMS technology has matured over recent years, the link between microscopy imaging currently used by pathologists and MS-based molecular imaging has not been established.Methods
We adapted the Vanderbilt University Tissue Core workflow for IMS into a web-based system that facilitates remote collaboration. The platform was designed to perform within acceptable web response times for viewing, annotating, and processing high resolution microscopy images.Results
We describe a microscopy-driven approach to tissue analysis by IMS.Conclusion
The Pathology Interface for Mass Spectrometry is designed to provide clinical access to IMS technology and deliver enhanced diagnostic value.
SUBMITTER: Norris JL
PROVIDER: S-EPMC4837791 | biostudies-literature |
REPOSITORIES: biostudies-literature
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