Ontology highlight
ABSTRACT:
SUBMITTER: Radzio J
PROVIDER: S-EPMC4837911 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Radzio Jessica J Henning Tara T Jenkins Leecresia L Ellis Shanon S Farshy Carol C Phillips Christi C Holder Angela A Kuklenyik Susan S Dinh Chuong C Hanson Debra D McNicholl Janet J Heneine Walid W Papp John J Kersh Ellen N EN García-Lerma J Gerardo JG
The Journal of infectious diseases 20160106 10
Genital inflammation associated with sexually transmitted infections increases susceptibility to human immunodeficiency virus (HIV), but it is unclear whether the increased risk can reduce the efficacy of pre-exposure prophylaxis (PrEP). We investigated whether coinfection of macaques with Chlamydia trachomatis and Trichomonas vaginalis decreases the prophylactic efficacy of oral emtricitabine (FTC)/tenofovir disoproxil fumarate (TDF). Macaques were exposed to simian/human immunodeficiency virus ...[more]