Comparative In Vivo Effects of Hemoglobin-Based Oxygen Carriers (HBOC) with Varying Prooxidant and Physiological Reactivity.
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ABSTRACT:
SUBMITTER: Toma VA
PROVIDER: S-EPMC4838227 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
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Comparative In Vivo Effects of Hemoglobin-Based Oxygen Carriers (HBOC) with Varying Prooxidant and Physiological Reactivity.
Toma Vlad Al VA Farcaș Anca D AD Roman Ioana I Sevastre Bogdan B Hathazi Denisa D Scurtu Florina F Damian Grigore G Silaghi-Dumitrescu Radu R
PloS one 20160420 4
A series of hemoglobin-based oxygen carrier candidates (HBOC), previously noted for their differences in prooxidative and physiological reactivity, were compared in terms of the negative effects displayed upon injection in Wistar rats. At the concentrations tested, antioxidant strategies based on albumin as well as based on rubrerythrin appear to offer observable physiological advantages. ...[more]
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