Test-retest reproducibility of neurochemical profiles with short-echo, single-voxel MR spectroscopy at 3T and 7T.
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ABSTRACT:
SUBMITTER: Terpstra M
PROVIDER: S-EPMC4846596 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
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Test-retest reproducibility of neurochemical profiles with short-echo, single-voxel MR spectroscopy at 3T and 7T.
Terpstra Melissa M Cheong Ian I Lyu Tianmeng T Deelchand Dinesh K DK Emir Uzay E UE Bednařík Petr P Eberly Lynn E LE Öz Gülin G
Magnetic resonance in medicine 20151026 4
<h4>Purpose</h4>To determine the test-retest reproducibility of neurochemical concentrations obtained with a highly optimized, short-echo, single-voxel proton MR spectroscopy (MRS) pulse sequence at 3T and 7T using state-of-the-art hardware.<h4>Methods</h4>A semi-LASER sequence (echo time = 26-28 ms) was used to acquire spectra from the posterior cingulate and cerebellum at 3T and 7T from six healthy volunteers who were scanned four times weekly on both scanners. Spectra were quantified with LCM ...[more]
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