Ontology highlight
ABSTRACT:
SUBMITTER: Sun L
PROVIDER: S-EPMC4848538 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Sun Libei L Yu Tong T Guo Jilong J Zhang Zhaobin Z Hu Ying Y Xiao Xuan X Sun Yingli Y Xiao Han H Li Junyu J Zhu Desheng D Sai Linlin L Li Jun J
Scientific reports 20160428
The estrogenicity of parabens at human exposure levels has become a focus of concern due to the debate over whether the estrogenicity of parabens is strong enough to play a role in the increased incidence of breast cancer. In this study, the uterotrophic activities of methylparaben (MP) and ethylparaben (EP) at doses close to the acceptable daily intake as allocated by JECFA were demonstrated in immature Sprague-Dawley rats by intragastric administration, and up-regulations of estrogen-responsiv ...[more]