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Molecularly Responsive Binding through Co-occupation of Binding Space: A Lock-Key Story.


ABSTRACT: When two guest molecules co-occupy a binding pocket of a water-soluble host, the first guest could be used as a signal molecule to turn on the binding of the second. This type of molecularly responsive binding strongly depends on the size of the two guests and the location of the signal molecule.

SUBMITTER: Awino JK 

PROVIDER: S-EPMC4849124 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature

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Molecularly Responsive Binding through Co-occupation of Binding Space: A Lock-Key Story.

Awino Joseph K JK   Hu Lan L   Zhao Yan Y  

Organic letters 20160322 7


When two guest molecules co-occupy a binding pocket of a water-soluble host, the first guest could be used as a signal molecule to turn on the binding of the second. This type of molecularly responsive binding strongly depends on the size of the two guests and the location of the signal molecule. ...[more]

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