Ontology highlight
ABSTRACT:
SUBMITTER: Slatter TL
PROVIDER: S-EPMC4858134 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Slatter Tania L TL Hsia Howard H Samaranayaka Ari A Sykes Peter P Clow William Bill WB Devenish Celia J CJ Sutton Tim T Royds Janice A JA Ip Philip P PP Cheung Annie N AN Hung Noelyn Anne NA
The journal of pathology. Clinical research 20150316 2
Uterine smooth muscle tumours of uncertain malignant potential (STUMP) are diagnostically and clinically challenging. The alternative lengthening of telomeres (ALT) telomere maintenance mechanism is associated with poor survival in soft tissue leiomyosarcoma. Time to first recurrence and survival were known for 18 STUMP and 43 leiomyosarcomata (LMS). These were screened for ALT telomere maintenance by the presence of ALT-associated PML bodies (APBs) and for changes associated with the ALT phenot ...[more]