Ontology highlight
ABSTRACT:
SUBMITTER: Deangelo DJ
PROVIDER: S-EPMC4860003 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Deangelo Daniel J DJ Neuberg Donna D Amrein Philip C PC Berchuck Jacob J Wadleigh Martha M Sirulnik L Andres LA Galinsky Ilene I Golub Todd T Stegmaier Kimberly K Stone Richard M RM
Leukemia research 20131105 4
Novel therapies for the treatment of acute myeloid leukemia are required to overcome disease resistance and to provide potentially less toxic therapies for older adults. Prior clinical trials involving patients with non-small cell lung cancer have demonstrated the safety and biologic activity of the administration of EGFR inhibitors in carefully selected patients. The potential efficacy of this approach in patients with acute myeloid leukemia is unknown. The effects of gefitinib on differentiati ...[more]