Ontology highlight
ABSTRACT:
SUBMITTER: Singhvi A
PROVIDER: S-EPMC4860081 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Singhvi Aakanksha A Liu Bingqian B Friedman Christine J CJ Fong Jennifer J Lu Yun Y Huang Xin-Yun XY Shaham Shai S
Cell 20160407 4
Neurons receive input from the outside world or from other neurons through neuronal receptive endings (NREs). Glia envelop NREs to create specialized microenvironments; however, glial functions at these sites are poorly understood. Here, we report a molecular mechanism by which glia control NRE shape and associated animal behavior. The C. elegans AMsh glial cell ensheathes the NREs of 12 neurons, including the thermosensory neuron AFD. KCC-3, a K/Cl transporter, localizes specifically to a glial ...[more]