MicroRNAs Regulate Host Immune Response and Pathogenesis During Influenza Infection in Rhesus Macaques.
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ABSTRACT:
SUBMITTER: Rivera A
PROVIDER: S-EPMC4860667 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
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microRNAs Regulate Host Immune Response and Pathogenesis During Influenza Infection in Rhesus Macaques.
Rivera Andrea A Barr Tasha T Rais Maham M Engelmann Flora F Messaoudi Ilhem I
Viral immunology 20160323 4
microRNAs (miRNAs) are small noncoding RNAs that are key regulators of biological processes, including the immune response to viral infections. Differential expression levels of cellular miRNAs and their predicted targets have been described in the lungs of H1N1-infected BALB/c mice, the lungs of H5N1 influenza-infected cynomolgus macaques, and in peripheral blood mononuclear cells (PBMCs) of critically ill patients infected with 2009 pandemic H1N1. However, a longitudinal analysis of changes in ...[more]
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