Ontology highlight
ABSTRACT:
SUBMITTER: Artan M
PROVIDER: S-EPMC4863736 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Genes & development 20160428 9
Environmental fluctuations influence organismal aging by affecting various regulatory systems. One such system involves sensory neurons, which affect life span in many species. However, how sensory neurons coordinate organismal aging in response to changes in environmental signals remains elusive. Here, we found that a subset of sensory neurons shortens Caenorhabditis elegans' life span by differentially regulating the expression of a specific insulin-like peptide (ILP), INS-6. Notably, treatmen ...[more]