Ontology highlight
ABSTRACT:
SUBMITTER: Musatov A
PROVIDER: S-EPMC4867122 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Musatov Andrej A Varhač Rastislav R Hosler Jonathan P JP Sedlák Erik E
Biochimie 20160226
Delipidation of detergent-solubilized cytochrome c oxidase isolated from Rhodobacter sphaeroides (Rbs-CcO) has no apparent structural and/or functional effect on the protein, however affects its resistance against thermal or chemical denaturation. Phospholipase A2 (PLA2) hydrolysis of phospholipids that are co-purified with the enzyme removes all but two tightly bound phosphatidylethanolamines. Replacement of the removed phospholipids with nonionic detergent decreases both thermal stability of t ...[more]