Ontology highlight
ABSTRACT:
SUBMITTER: Lore NI
PROVIDER: S-EPMC4870500 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Lorè Nicola Ivan NI Cigana Cristina C Riva Camilla C De Fino Ida I Nonis Alessandro A Spagnuolo Lorenza L Sipione Barbara B Cariani Lisa L Girelli Daniela D Rossi Giacomo G Basso Veronica V Colombo Carla C Mondino Anna A Bragonzi Alessandra A
Scientific reports 20160518
Resistance and tolerance mechanisms participate to the interplay between host and pathogens. IL-17-mediated response has been shown to be crucial for host resistance to respiratory infections, whereas its role in host tolerance during chronic airway colonization is still unclear. Here, we investigated whether IL-17-mediated response modulates mechanisms of host tolerance during airways chronic infection by P. aeruginosa. First, we found that IL-17A levels were sustained in mice at both early and ...[more]