Ontology highlight
ABSTRACT:
SUBMITTER: Binan L
PROVIDER: S-EPMC4876456 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Nature communications 20160520
The ability to conduct image-based, non-invasive cell tagging, independent of genetic engineering, is key to cell biology applications. Here we introduce cell labelling via photobleaching (CLaP), a method that enables instant, specific tagging of individual cells based on a wide array of criteria such as shape, behaviour or positional information. CLaP uses laser illumination to crosslink biotin onto the plasma membrane, coupled with streptavidin conjugates to label individual cells for genomic, ...[more]