Ontology highlight
ABSTRACT:
SUBMITTER: Qian C
PROVIDER: S-EPMC4876629 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Theranostics 20160428 7
Stimuli-responsive and imaging-guided drug delivery systems hold vast promise for enhancement of therapeutic efficacy. Here we report an adenosine-5'-triphosphate (ATP)-responsive and near-infrared (NIR)-emissive conjugated polymer-based nanocarrier for the controlled release of anticancer drugs and real-time imaging. We demonstrate that the conjugated polymeric nanocarriers functionalized with phenylboronic acid tags on surface as binding sites for ATP could be converted to the water-soluble co ...[more]