Ontology highlight
ABSTRACT:
SUBMITTER: Graham DM
PROVIDER: S-EPMC4879165 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Graham Donna M DM Coyle Vicky M VM Kennedy Richard D RD Wilson Richard H RH
Current colorectal cancer reports 20160418
Development of colorectal cancer occurs via a number of key pathways, with the clinicopathological features of specific subgroups being driven by underlying molecular changes. Mutations in key genes within the network of signalling pathways have been identified; however, therapeutic strategies to target these aberrations remain limited. As understanding of the biology of colorectal cancer has improved, this has led to a move toward broader genomic testing, collaborative research and innovative, ...[more]