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First genome sequences of buffalo coronavirus from water buffaloes in Bangladesh.

ABSTRACT: We report the complete genome sequences of a buffalo coronavirus (BufCoV HKU26) detected from the faecal samples of two domestic water buffaloes (Bubalus bubalis) in Bangladesh. They possessed 98-99% nucleotide identities to bovine coronavirus (BCoV) genomes, supporting BufCoV HKU26 as a member of Betacoronavirus 1. Nevertheless, BufCoV HKU26 possessed distinct accessory proteins between spike and envelope compared to BCoV. Sugar-binding residues in the N-terminal domain of S protein in BCoV are conserved in BufCoV HKU26.

SUBMITTER: Lau SK

PROVIDER: S-EPMC4879238 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature

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First genome sequences of buffalo coronavirus from water buffaloes in Bangladesh.

Lau S K P SK Tsang A K L AK Shakeel Ahmed S S Mahbub Alam M M Ahmed Z Z Wong P-C PC Yuen K-Y KY Woo P C Y PC

New microbes and new infections 20160303

We report the complete genome sequences of a buffalo coronavirus (BufCoV HKU26) detected from the faecal samples of two domestic water buffaloes (Bubalus bubalis) in Bangladesh. They possessed 98-99% nucleotide identities to bovine coronavirus (BCoV) genomes, supporting BufCoV HKU26 as a member of Betacoronavirus 1. Nevertheless, BufCoV HKU26 possessed distinct accessory proteins between spike and envelope compared to BCoV. Sugar-binding residues in the N-terminal domain of S protein in BCoV are ...[more]

PMID: 27274850

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