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Draft genome of the river water buffalo.

ABSTRACT: Water buffalo (Bubalus bubalis), a large-sized member of the Bovidae family, is considered as an important livestock species throughout Southeast Asia. In order to better understand the molecular basis of buffalo improvement and breeding, we sequenced and assembled the genome (2n=50) of a river buffalo species Bubalus bubalis from Bangladesh. Its genome size is 2.77 Gb, with a contig N50 of 25 kb and the scaffold N50 of 6.9 Mbp. Based on the assembled genome, we annotated 24,613 genes for future functional genomics studies. Phylogenetic tree analysis of cattle and water buffalo lineages showed that they diverged about 5.8-9.8 million years ago. Our findings provide an insight into the water buffalo genome which will contribute in further research on buffalo such as molecular breeding, understanding complex traits, conservation, and biodiversity.

SUBMITTER: Mintoo AA

PROVIDER: S-EPMC6434576 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature

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Draft genome of the river water buffalo.

Mintoo Abdul Awal AA Zhang Hailin H Chen Chunhai C Moniruzzaman Mohammad M Deng Tingxian T Anam Mahbub M Emdadul Huque Quazi Mohammad QM Guang Xuanmin X Wang Ping P Zhong Zhen Z Han Pengfei P Khatun Asma A Awal Tabith M TM Gao Qiang Q Liang Xianwei X

Ecology and evolution 20190218 6

Water buffalo (Bubalus bubalis), a large-sized member of the Bovidae family, is considered as an important livestock species throughout Southeast Asia. In order to better understand the molecular basis of buffalo improvement and breeding, we sequenced and assembled the genome (2n=50) of a river buffalo species Bubalus bubalis from Bangladesh. Its genome size is 2.77 Gb, with a contig N50 of 25 kb and the scaffold N50 of 6.9 Mbp. Based on the assembled genome, we annotated 24,613 ge ...[more]

PMID: 30962899

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