Polyphosphate and acidocalcisomes.
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ABSTRACT:
SUBMITTER: Lander N
PROVIDER: S-EPMC4879816 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Publications
Polyphosphate and acidocalcisomes.
Lander Noelia N Cordeiro Ciro C Huang Guozhong G Docampo Roberto R
Biochemical Society transactions 20160201 1
Inorganic polyphosphate (polyP) accumulates in acidocalcisomes, acidic calcium stores that have been found from bacteria to human cells. Proton pumps, such as the vacuolar proton pyrophosphatase (V-H(+)-PPase or VP1), the vacuolar proton ATPase (V-H(+)-ATPase) or both, maintain their acidity. A vacuolar transporter chaperone (VTC) complex is involved in the synthesis and translocation of polyP to these organelles in several eukaryotes, such as yeast, trypanosomatids, Apicomplexan and algae. Stud ...[more]
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