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Neuroenhancement of the aging brain: restoring skill acquisition in old subjects.

ABSTRACT: OBJECTIVE:Decline in cognitive functions, including impaired acquisition of novel skills, is a feature of older age that impacts activities of daily living, independence, and integration in modern societies. METHODS:We tested whether the acquisition of a complex motor skill can be enhanced in old subjects by the application of transcranial direct current stimulation (tDCS) to the motor cortex. RESULTS:The main finding was that old participants experienced substantial improvements when training was applied concurrent with tDCS, with effects lasting for at least 24 hours. INTERPRETATION:These results suggest noninvasive brain stimulation as a promising and safe tool to potentially assist functional independence of aged individuals in daily life.

SUBMITTER: Zimerman M

PROVIDER: S-EPMC4880032 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature

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Neuroenhancement of the aging brain: restoring skill acquisition in old subjects.

Zimerman Máximo M Nitsch Marie M Giraux Pascal P Gerloff Christian C Cohen Leonardo G LG Hummel Friedhelm C FC

Annals of neurology 20121207 1

<h4>Objective</h4>Decline in cognitive functions, including impaired acquisition of novel skills, is a feature of older age that impacts activities of daily living, independence, and integration in modern societies.<h4>Methods</h4>We tested whether the acquisition of a complex motor skill can be enhanced in old subjects by the application of transcranial direct current stimulation (tDCS) to the motor cortex.<h4>Results</h4>The main finding was that old participants experienced substantial improv ...[more]

PMID: 23225625

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