Ontology highlight
ABSTRACT:
SUBMITTER: Ward-Kavanagh LK
PROVIDER: S-EPMC4882112 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Ward-Kavanagh Lindsay K LK Lin Wai Wai WW Šedý John R JR Ware Carl F CF
Immunity 20160501 5
Cytokines related to tumor necrosis factor (TNF) provide a communication network essential for coordinating multiple cell types into an effective host defense system against pathogens and malignant cells. The pathways controlled by the TNF superfamily differentiate both innate and adaptive immune cells and modulate stromal cells into microenvironments conducive to host defenses. Members of the TNF receptor superfamily activate diverse cellular functions from the production of type 1 interferons ...[more]