Ontology highlight
ABSTRACT:
SUBMITTER: Lin KH
PROVIDER: S-EPMC4886675 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Lin Kuan-Hung KH Ho Ya-Hsuan YH Chiang Jui-Chung JC Li Meng-Wei MW Lin Shi-Hung SH Chen Wei-Min WM Chiang Chi-Ling CL Lin Yu-Nung YN Yang Ya-Jan YJ Chen Chiung-Nien CN Lu Jenher J Huang Chang-Jen CJ Tigyi Gabor G Yao Chao-Ling CL Lee Hsinyu H
Scientific reports 20160531
Lysophosphatidic acid (LPA), a growth factor-like phospholipid, regulates numerous physiological functions, including cell proliferation and differentiation. In a previous study, we have demonstrated that LPA activates erythropoiesis by activating the LPA 3 receptor subtype (LPA3) under erythropoietin (EPO) induction. In the present study, we applied a pharmacological approach to further elucidate the functions of LPA receptors during red blood cell (RBC) differentiation. In K562 human erythrole ...[more]