Ontology highlight
ABSTRACT:
SUBMITTER: Visser M
PROVIDER: S-EPMC4890495 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Visser Marike M Bester Rachelle R Burger Johan T JT Maree Hans J HJ
Virology journal 20160602
<h4>Background</h4>The use of next-generation sequencing has become an established method for virus detection. Efficient study design for accurate detection relies on the optimal amount of data representing a significant portion of a virus genome.<h4>Findings</h4>In this study, genome coverage at different sequencing depths was determined for a number of viruses, viroids, hosts and sequencing library types, using both read-mapping and de novo assembly-based approaches. The results highlighted th ...[more]