Ontology highlight
ABSTRACT:
SUBMITTER: Hallac RR
PROVIDER: S-EPMC4891499 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Hallac Rami R RR Zhou Heling H Pidikiti Rajesh R Song Kwang K Solberg Timothy T Kodibagkar Vikram D VD Peschke Peter P Mason Ralph P RP
British journal of cancer 20160503 11
<h4>Background</h4>Dynamic contrast-enhanced (DCE) MRI may provide prognostic insights into tumour radiation response. This study examined quantitative DCE MRI parameters in rat tumours, as potential biomarkers of tumour growth delay following single high-dose irradiation.<h4>Methods</h4>Dunning R3327-AT1 prostate tumours were evaluated by DCE MRI following intravenous injection of Gd-DTPA. The next day tumours were irradiated (single dose of 30 Gy), while animals breathed air (n=4) or oxygen (n ...[more]