Ontology highlight
ABSTRACT:
SUBMITTER: Buishand FO
PROVIDER: S-EPMC4892226 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Stem cells and development 20160505 11
The long-term prognosis after surgical resection of malignant insulinoma (INS) is poor. Novel adjuvant therapies, specifically targeting cancer stem cells (CSCs), are warranted. Therefore, the goal of this study was to characterize and target putative INS CSCs. Using fluorescence-activated cell sorting, human INS cell line CM and pancreatic carcinoid cell line BON1 were screened for the presence of stem cell-associated markers. CD90, CD166, and GD2 were identified as potential CSC markers. Only ...[more]