Ontology highlight
ABSTRACT:
SUBMITTER: Sen D
PROVIDER: S-EPMC4893203 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Sen Debasish D SoRelle Elliott D ED Liba Orly O Dalal Roopa R Paulus Yannis M YM Kim Tae-Wan TW Moshfeghi Darius M DM de la Zerda Adam A
Journal of biomedical optics 20160601 6
Optical coherence tomography (OCT) is a noninvasive interferometric imaging modality providing anatomical information at depths of millimeters and a resolution of micrometers. Conventional OCT images limit our knowledge to anatomical structures alone, without any contrast enhancement. Therefore, here we have, for the first time, optimized an OCT-based contrast-enhanced imaging system for imaging single cells and blood vessels in vivo inside the living mouse retina at subnanomolar sensitivity. We ...[more]