Ontology highlight
ABSTRACT:
SUBMITTER: Graf TN
PROVIDER: S-EPMC4893890 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Graf Tyler N TN Cech Nadja B NB Polyak Stephen J SJ Oberlies Nicholas H NH
Journal of pharmaceutical and biomedical analysis 20160422
Validated methods are needed for the analysis of natural product secondary metabolites. These methods are particularly important to translate in vitro observations to in vivo studies. Herein, a method is reported for the analysis of the key secondary metabolites, a series of flavonolignans and a flavonoid, from an extract prepared from the seeds of milk thistle [Silybum marianum (L.) Gaertn. (Asteraceae)]. This report represents the first UHPLC MS-MS method validated for quantitative analysis of ...[more]