Ontology highlight
ABSTRACT:
SUBMITTER: Yu L
PROVIDER: S-EPMC4895301 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Yu Ling L Yan Mingquan M Simkin Jennifer J Ketcham Paulina D PD Leininger Eric E Han Manjong M Muneoka Ken K
Regeneration (Oxford, England) 20140601 3
The regenerating mouse digit tip is a unique model for investigating blastema formation and epimorphic regeneration in mammals. The blastema is characteristically avascular and we previously reported that blastema expression of a known anti-angiogenic factor gene, Pedf, correlated with a successful regenerative response (Yu, L., Han, M., Yan, M., Lee, E. C., Lee, J. & Muneoka, K. (2010). BMP signaling induces digit regeneration in neonatal mice. Development, 137, 551-559). Here we show that duri ...[more]