Ontology highlight
ABSTRACT:
SUBMITTER: Vo KT
PROVIDER: S-EPMC4896001 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Vo Kieuhoa T KT Matthay Katherine K KK DuBois Steven G SG
Clinical sarcoma research 20160607
Sarcomas are a heterogeneous group of mesenchymal malignancies. In recent years, studies have demonstrated that inhibition of angiogenic pathways or disruption of established vasculature can attenuate the growth of sarcomas. However, when used as monotherapy in the clinical setting, these targeted antiangiogenic agents have only provided modest survival benefits in some sarcoma subtypes, and have not been efficacious in others. Preclinical and early clinical data suggest that the addition of con ...[more]