Greater hippocampal volume is associated with PTSD treatment response.
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ABSTRACT:
SUBMITTER: Rubin M
PROVIDER: S-EPMC4896219 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Publications
Greater hippocampal volume is associated with PTSD treatment response.
Rubin Mikael M Shvil Erel E Papini Santiago S Chhetry Binod T BT Helpman Liat L Markowitz John C JC Mann J John JJ Neria Yuval Y
Psychiatry research. Neuroimaging 20160504
Previous research associates smaller hippocampal volume with posttraumatic stress disorder (PTSD). It is unclear, however, whether treatment affects hippocampal volume or vice versa. Seventy-six subjects, 40 PTSD patients and 36 matched trauma-exposed healthy resilient controls, underwent clinical assessments and magnetic resonance imaging (MRI) at baseline, and 10 weeks later, during which PTSD patients completed ten weeks of Prolonged Exposure (PE) treatment. The resilient controls and treatme ...[more]
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