Ontology highlight
ABSTRACT:
SUBMITTER: Eslami-Mossallam B
PROVIDER: S-EPMC4896621 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Eslami-Mossallam Behrouz B Schram Raoul D RD Tompitak Marco M van Noort John J Schiessel Helmut H
PloS one 20160607 6
Eukaryotic DNA is strongly bent inside fundamental packaging units: the nucleosomes. It is known that their positions are strongly influenced by the mechanical properties of the underlying DNA sequence. Here we discuss the possibility that these mechanical properties and the concomitant nucleosome positions are not just a side product of the given DNA sequence, e.g. that of the genes, but that a mechanical evolution of DNA molecules might have taken place. We first demonstrate the possibility of ...[more]