Ontology highlight
ABSTRACT:
SUBMITTER: Fura JM
PROVIDER: S-EPMC4898660 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Fura Jonathan M JM Pidgeon Sean E SE Birabaharan Morgan M Pires Marcos M MM
ACS infectious diseases 20160202 4
The number of antibiotic-resistant bacterial infections has increased dramatically over the past decade. To combat these pathogens, novel antimicrobial strategies must be explored and developed. We previously reported a strategy based on hapten-modified cell wall analogues to induce recruitment of endogenous antibodies to bacterial cell surfaces. Cell surface remodeling using unnatural single d-amino acid cell wall analogues led to modification at the C-terminus of the peptidoglycan stem peptide ...[more]