Ontology highlight
ABSTRACT:
SUBMITTER: Bancroft T
PROVIDER: S-EPMC4899275 | biostudies-literature | 2016 Jun-Jul
REPOSITORIES: biostudies-literature
Bancroft Tara T Dillon Myles B C MB da Silva Antunes Ricardo R Paul Sinu S Peters Bjoern B Crotty Shane S Lindestam Arlehamn Cecilia S CS Sette Alessandro A
Cellular immunology 20160514
The recent increase in cases of whooping cough among teenagers in the US suggests that the acellular Bordetella pertussis vaccine (aP) that became standard in the mid 1990s might be relatively less effective than the whole-bacteria formulation (wP) previously used since the 1950s. To understand this effect, we compared antibody and T cell responses to a booster immunization in subjects who received either the wP or aP vaccine as their initial priming dose in childhood. Antibody responses in wP- ...[more]