Ontology highlight
ABSTRACT:
SUBMITTER: Zhang H
PROVIDER: S-EPMC4899488 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Zhang Huimin H Seward Christopher H CH Wu Zuowei Z Ye Huiyan H Feng Youjun Y
Science bulletin 20160519
Polymyxin acts as an ultimate line of refuge against the severe infections by multidrug-resistant Gram-negative pathogens. This conventional idea is challenged dramatically by the recent discovery of mobile colistin resistance gene (<i>mcr</i>-<i>1</i>) is prevalent in food animals and human beings worldwide. More importantly, the <i>mcr</i>-<i>1</i> gene was found to be co-localized with other antibiotic resistance genes, raising the possibility that super-bugs with pan-drug resistance are emer ...[more]