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ABSTRACT: Background
Given the early age of onset (AOO) of psychotic disorders, it has been assumed that psychotic experiences (PEs) would have a similar early AOO. The aims of this study were to describe (a) the AOO distribution of PEs, (b) the projected lifetime risk of PEs, and (c) the associations of PE AOO with selected PE features.Methods
Data came from the WHO World Mental Health (WMH) surveys. A total of 31 261 adult respondents across 18 countries were assessed for lifetime prevalence of PE. Projected lifetime risk (at age 75 years) was estimated using a 2-part actuarial method. AOO distributions were described for the observed and projected estimates. We examined associations of AOO with PE type metric and annualized PE frequency.Results
Projected lifetime risk for PEs was 7.8% (SE = 0.3), slightly higher than lifetime prevalence (5.8%, SE = 0.2). The median (interquartile range; IQR) AOO based on projected lifetime estimates was 26 (17-41) years, indicating that PEs commence across a wide age range. The AOO distributions for PEs did not differ by sex. Early AOO was positively associated with number of PE types (F = 14.1, P < .001) but negatively associated with annualized PE frequency rates (F = 8.0, P < .001).Discussion
While most people with lifetime PEs have first onsets in adolescence or young adulthood, projected estimates indicate that nearly a quarter of first onsets occur after age 40 years. The extent to which late onset PEs are associated with (a) late onset mental disorders or (b) declining cognitive and/or sensory function need further research.
SUBMITTER: McGrath JJ
PROVIDER: S-EPMC4903064 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
McGrath John J JJ Saha Sukanta S Al-Hamzawi Ali O AO Alonso Jordi J Andrade Laura L Borges Guilherme G Bromet Evelyn J EJ Oakley Browne Mark M Bruffaerts Ronny R Caldas de Almeida Jose M JM Fayyad John J Florescu Silvia S de Girolamo Giovanni G Gureje Oye O Hu Chiyi C de Jonge Peter P Kovess-Masfety Viviane V Lepine Jean Pierre JP Lim Carmen C W CC Navarro-Mateu Fernando F Piazza Maria M Sampson Nancy N Posada-Villa José J Kendler Kenneth S KS Kessler Ronald C RC
Schizophrenia bulletin 20160402 4
<h4>Background</h4>Given the early age of onset (AOO) of psychotic disorders, it has been assumed that psychotic experiences (PEs) would have a similar early AOO. The aims of this study were to describe (a) the AOO distribution of PEs, (b) the projected lifetime risk of PEs, and (c) the associations of PE AOO with selected PE features.<h4>Methods</h4>Data came from the WHO World Mental Health (WMH) surveys. A total of 31 261 adult respondents across 18 countries were assessed for lifetime preval ...[more]