Ontology highlight
ABSTRACT:
SUBMITTER: Sugahara G
PROVIDER: S-EPMC4905851 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Sugahara Go G Kamiie Junichi J Kobayashi Ryosuke R Mineshige Takayuki T Shirota Kinji K
The Journal of veterinary medical science 20160206 5
Phospholipase A2 receptor (PLA2R) expressed in human podocytes has been highlighted as a causative autoantigen of human idiopathic membranous nephropathy. However, its expression was found to be minimal or absent in murine and rat podocytes. In this study, immunofluorescence revealed the expression of PLA2R in the glomerular podocytes in the kidney tissue sections of dogs. We then attempted to culture canine podocytes and investigate the expression of PLA2R in these cells. Glomeruli were isolate ...[more]